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Healthy Skepticism Library item: 9971

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Tuffs A.
Thalidomide: the true story?
BMJ 2007 May 5; 334:(7600):933
http://www.bmj.com/cgi/content/full/334/7600/933


Abstract:

A legal battle between the German media and the manufacturers of the drug thalidomide over the accuracy of a new television drama has thrust the 50 year old tragedy back into the headlines

One of the worst tragedies in the history of drug therapy began almost 50 years ago, on 1 October 1957, when thalidomide was introduced as a sleeping pill by the firm Grünenthal onto the West German market. The drug, prescribed and sold over the counter as Contergan in West Germany, was launched in almost 50 other countries, including the United Kingdom and Canada, mostly under licence. It had sedating effects and seemed to be well tolerated and without toxic side effects, even in pregnancy. Two years later the link between the pill and serious malformations in newborn babies was discovered. Worldwide, about 12 000 children with limb deformations were born (no cases occurred in the United States because of a stricter drug safety law, diligently administered by the Food and Drug Administration).

This anniversary should have been accompanied by the broadcasting of the television drama “Eine einzige Tablette” (“Just one . . .

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909