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Healthy Skepticism Library item: 9285

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Dowie J.
Transparency in NICE
BMJ 2007 Apr 7; 334:(7596):709
http://www.bmj.com/cgi/content/full/334/7596/709-a


Abstract:

Let’s open whole process of cost effective modelling

The National Institute for Health and Clinical Excellence (NICE) needs to go much further than allowing access to its modelling data.1 The whole cost effectiveness modelling process needs to be opened up to involvement by all stakeholders, and inspection by the public, as it happens. The independent group should be contracted to develop the one and only model that NICE will consider in its appraisal, and it should do so in full and continuous collaboration with all registered stakeholders and interested parties who sign up to the NICE guidelines. The model will be run with any alternative parameters suggested by various parties and the alternative results (along with their evidential basis) submitted to the appraisal committee in a single report. No subsequent questioning of, or submissions regarding, the model structure, the results, or the underlying principles would be accepted in the context of any particular case…

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909