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Healthy Skepticism Library item: 9246

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Cutler DM.
The demise of the blockbuster?
N Engl J Med 2007 Mar 29; 356:(13):1292-3
http://content.nejm.org/cgi/content/extract/356/13/1292


Abstract:

When Pfizer announced that it was halting clinical testing of its new cholesterol drug, torcetrapib, the company’s market value fell by $21 billion overnight. Ten thousand job cuts followed. The ongoing promise of nearly $3 billion in annual sales vanished when Merck pulled Vioxx (rofecoxib) from the shelves, and the company’s market value fell by $25 billion. For decades, blockbuster drugs have nourished Big Pharma, but it is increasingly uncertain whether they can be counted on to support the industry in the future.

Prescription medications are extremely costly to develop and market. The cost of bringing a new drug to . . .

Keywords:
MeSH Terms: Chemistry, Pharmaceutical/economics* Chemistry, Pharmaceutical/trends Commerce Drug Costs Drug Industry/economics* Economic Competition*/trends Humans Prescription Fees Prescriptions, Drug/economics United States

 

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Cases of wilful misrepresentation are a rarity in medical advertising. For every advertisement in which nonexistent doctors are called on to testify or deliberately irrelevant references are bunched up in [fine print], you will find a hundred or more whose greatest offenses are unquestioning enthusiasm and the skill to communicate it.

The best defence the physician can muster against this kind of advertising is a healthy skepticism and a willingness, not always apparent in the past, to do his homework. He must cultivate a flair for spotting the logical loophole, the invalid clinical trial, the unreliable or meaningless testimonial, the unneeded improvement and the unlikely claim. Above all, he must develop greater resistance to the lure of the fashionable and the new.
- Pierre R. Garai (advertising executive) 1963