Healthy Skepticism Library item: 8054
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Publication type: Journal Article
Koeth LM, Miller LA.
Evolving concepts of pharmaceutical company-sponsored surveillance studies.
Clin Infect Dis 2005 Aug 15; 41:
http://www.journals.uchicago.edu/CID/journal/issues/v41nS4/36167/36167.html
Abstract:
As a result of increasing bacterial resistance to antimicrobial agents, there is a need to conduct studies that monitor changes in susceptibility. In addition to studying the emergence and dissemination of antibacterial resistance, pharmaceutical companies perform surveillance studies for a number of reasons. As an example, the Alexander Project was conducted to study community-acquired respiratory infections internationally over 10 years. The project’s findings have been valuable in the study of antimicrobial resistance. The Alexander Project has also been instrumental in the study of the evolution of resistance genes and in predictions of future rates of resistance, as well as in establishing the importance of high-quality data, the complexity of the evolution of resistance, and the need to disseminate the results in a variety of formats. Although there has been a reduction in pharmaceutical company studies, consolidated efforts between industry, government, and private groups have increased. Future surveillance efforts by pharmaceutical companies will likely be more targeted and disease directed.
Keywords:
Publication Types:
Research Support, Non-U.S. Gov't
Review
MeSH Terms:
Bacteria/classification
Bacteria/drug effects
Bacterial Infections*/drug therapy
Bacterial Infections*/epidemiology
Bacterial Infections*/microbiology
Drug Industry*
Drug Resistance, Microbial*
Humans
International Cooperation
Population Surveillance*
Research/standards
Research/trends*
World Health
Notes:
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