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Healthy Skepticism Library item: 8020

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Wawruch M, Zikavska M, Wsolova L, Jezova D, Fialova D, Kunzo M, Kuzelova M, Lassanova M, Kruty P, Kriska M.
Perception of potentially inappropriate medication in elderly patients by Slovak physicians.
Pharmacoepidemiol Drug Saf 2006 Nov; 15:(11):829-34
http://www3.interscience.wiley.com/cgi-bin/abstract/112770125/ABSTRACT


Abstract:

PURPOSE: The aim of the present study was to determine the risk perception of potentially inappropriate drug treatment of elderly patients by Slovak physicians. In Slovakia, a list of such drugs is not available.

METHODS: The study sample consisted of 600 patients aged > or =65 years hospitalized at the Department of Internal Medicine in a Slovak general hospital between 1 December 2003 and 31 March 2005. The use of potentially inappropriate drugs at the time of hospital admission and discharge was compared. Potentially inappropriate drug use was defined by Beers 2003 criteria. In addition, 206 physicians were asked to mark the drugs that they considered potentially inappropriate for elderly patients out of a list provided in a questionnaire analysis.

RESULTS: Out of 600 patients 20.2% and 20% were treated with at least one potentially inappropriate drug at the time of hospital admission and discharge, respectively. Hospitalization had no significant influence on the number of potentially inappropriate medicines used. The most frequently prescribed potentially inappropriate drugs were digoxin >0.125 mg/day and ticlopidine. Out of 206 responding physicians only 4.9% considered ticlopidine as potentially inappropriate for elderly patient. On the other hand, more than 20% of respondents were aware of the potential inappropriateness of amitriptyline, diazepam and chlordiazepoxide. Mentioned drugs were observed in less than 2% of study population (n = 600).

CONCLUSIONS: The results of the questionnaire analysis in physicians as well as the prevalence of potentially inappropriate medication demonstrate that Slovak clinicians are aware of the risk of certain treatments in elderly patients.

Keywords:
elderly patient • potentially inappropriate medication • Beers 2003 criteria • questionnaire analysis • prescribing physicians • Slovakia • hospital admission and discharge Publication Types: Research Support, Non-U.S. Gov't MeSH Terms: Aged* Attitude of Health Personnel* Drug Therapy*/adverse effects Drug Therapy*/statistics & numerical data Drug Utilization/statistics & numerical data Education, Medical/standards Female Health Knowledge, Attitudes, Practice Health Services Needs and Demand Hospital Departments/statistics & numerical data Hospitalization*/statistics & numerical data Hospitals, General Humans Internal Medicine/statistics & numerical data Male Patient Selection* Physician's Practice Patterns/statistics & numerical data Physicians/psychology* Prescriptions, Drug/statistics & numerical data Questionnaires Retrospective Studies Risk Factors Slovakia

 

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...to influence multinational corporations effectively, the efforts of governments will have to be complemented by others, notably the many voluntary organisations that have shown they can effectively represent society’s public-health interests…
A small group known as Healthy Skepticism; formerly the Medical Lobby for Appropriate Marketing) has consistently and insistently drawn the attention of producers to promotional malpractice, calling for (and often securing) correction. These organisations [Healthy Skepticism, Médecins Sans Frontières and Health Action International] are small, but they are capable; they bear malice towards no one, and they are inscrutably honest. If industry is indeed persuaded to face up to its social responsibilities in the coming years it may well be because of these associations and others like them.
- Dukes MN. Accountability of the pharmaceutical industry. Lancet. 2002 Nov 23; 360(9346)1682-4.