Healthy Skepticism Library item: 7591
Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.
Publication type: Journal Article
de Lorgeril M, Salen P.
Cholesterol lowering and mortality: time for a new paradigm?
Nutr Metab Cardiovasc Dis 2006 Sep; 16:(6):387-90
http://linkinghub.elsevier.com/retrieve/pii/S0939-4753(06)00124-4
Abstract:
Sudden cardiac death is the main cause of cardiac mortality. Is blood cholesterol a determinant of sudden cardiac death? Does cholesterol lowering result in fewer sudden cardiac deaths? Answering these two questions may shed new light on the epidemiology of coronary heart disease and on prevention options. In fact, careful analysis of the available data, including randomised trials, indicates that, contrary to a widespread opinion, cholesterol lowering does not appear to be a very effective way of reducing cardiac and overall mortality in the general population.
Keywords:
MeSH Terms:
Anticholesteremic Agents/therapeutic use*
Cholesterol/blood*
Coronary Disease/mortality*
Death, Sudden, Cardiac/etiology*
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use
Risk Factors
Substances:
Anticholesteremic Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cholesterol
