Healthy Skepticism Library item: 6861
Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.
Publication type: Journal Article
Koepp R, Miles SH.
Meta-analysis of tacrine for Alzheimer disease: the influence of industry sponsors.
JAMA 1999 Jun 23-30; 281:(24):2287-8
http://jama.ama-assn.org/cgi/content/full/281/24/2287
Abstract:
The favourable meta-analysis of tacrine for treating Alzheimer disease did not consider the potential influence of corporate sponsorship on the reported studies. Studies without corporate support found no clinical effect. All but one of the manufacturer-supported studies found clinical benefit.
Keywords:
*letter to the editor/*analysis/Alzheimer disease/ corporate funding/ reporting of results/ drug company sponsored research/ relationship between researchers, academic institutions and industry/ clinical trials/ETHICAL ISSUES IN PROMOTION: LINKS BETWEEN HEALTH PROFESSIONALS AND INDUSTRY/INFLUENCE OF PROMOTION: OUTCOME OF CLINICAL TRIALS/INFLUENCE OF PROMOTION: PUBLICATION/SPONSORSHIP: RESEARCH
Alzheimer Disease/drug therapy*
Biomedical Research*
Cholinesterase Inhibitors/therapeutic use*
Conflict of Interest*
Drug Industry*
Humans
Meta-Analysis*
Research Support*
Research Support, Non-U.S. Gov't
Tacrine/therapeutic use*
Therapeutic Human Experimentation*
