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Healthy Skepticism Library item: 6844

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Dieppe P, Chard J, Tallon D, Egger M.
Funding clinical research.
Lancet 1999 May 8; 353:(9164):1626


Abstract:

Industrial sponsorship of a study correlated positively with the likelihood of an outcome in favour of the sponsors’ treatment. The same trend holds true at the level of meta-analyses of clinical trials published in eight high-impact medical journals. Industrial funding of trials has undue influence on the research agenda and distorts the body of published evidence.

Keywords:
*letter to the editor/*analytic survey/clinical trials/ drug company sponsored research/ reporting of results/INFLUENCE OF PROMOTION: OUTCOME OF CLINICAL TRIALS/PROMOTION DISGUISED: CLINICAL TRIALS/SPONSORSHIP: RESEARCH Clinical Trials/economics* Clinical Trials/trends Drug Industry* Female Humans Public Policy Research Support/economics* Research Support/trends

 

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Cases of wilful misrepresentation are a rarity in medical advertising. For every advertisement in which nonexistent doctors are called on to testify or deliberately irrelevant references are bunched up in [fine print], you will find a hundred or more whose greatest offenses are unquestioning enthusiasm and the skill to communicate it.

The best defence the physician can muster against this kind of advertising is a healthy skepticism and a willingness, not always apparent in the past, to do his homework. He must cultivate a flair for spotting the logical loophole, the invalid clinical trial, the unreliable or meaningless testimonial, the unneeded improvement and the unlikely claim. Above all, he must develop greater resistance to the lure of the fashionable and the new.
- Pierre R. Garai (advertising executive) 1963