Healthy Skepticism Library item: 5668
Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.
Publication type: Journal Article
Collis MC.
Integrative pharmacology and drug discovery--is the tide finally turning?
Nat Rev Drug Discov 2006 May 01; 5:(5):377-9
http://www.nature.com/nrd/journal/v5/n5/abs/nrd2036.html;jsessionid=2E66E474982DC1C9B107D97A21F5C060
Abstract:
In vivo animal experiments are essential (and a regulatory requirement) to demonstrate the potential efficacy, safety and pharmacodynamic/pharmacokinetic profile of candidate drugs. However, the number of pharmacologists (and other bioscientists) with integrative (in vivo) pharmacology skills has been in decline for a number of years, as have the opportunities for students to learn such skills. This article reviews some recent initiatives that are underway to rebuild this essential skills base in the United Kingdom and the United States. Partnerships between industry and national funders of research and education have proved to be a particularly effective approach to support this strategically important area of biological science.
Keywords:
Animals
Career Choice
Chemistry, Pharmaceutical
Drug Evaluation, Preclinical
Drug Industry
Great Britain
Humans
Pharmacology/education*
Pharmacology/trends
Physiology/education*
Physiology/trends
Research
United States
Universities
