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Healthy Skepticism Library item: 5422

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Fitzgerald GA.
Coxibs and cardiovascular disease.
N Engl J Med 2004 Oct 21; 351:(17):1709-11
http://content.nejm.org/cgi/content/extract/351/17/1709

Keywords:
Adverse Drug Reaction Reporting Systems Anti-Inflammatory Agents, Non-Steroidal/adverse effects Anti-Inflammatory Agents, Non-Steroidal/pharmacology Cardiovascular Diseases/chemically induced* Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Cyclooxygenase Inhibitors/adverse effects* Cyclooxygenase Inhibitors/pharmacology Drug Approval* Drug Industry Epoprostenol/antagonists & inhibitors Gastrointestinal Diseases/chemically induced Humans Isoenzymes/antagonists & inhibitors Isoenzymes/metabolism Isoxazoles/adverse effects Lactones/adverse effects* Lactones/pharmacology Membrane Proteins Naproxen/adverse effects Prostaglandin-Endoperoxide Synthases/metabolism Pyrazoles Risk Sulfonamides/adverse effects Sulfonamides/pharmacology Sulfones Thromboxane A2/biosynthesis United States United States Food and Drug Administration

 

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Cases of wilful misrepresentation are a rarity in medical advertising. For every advertisement in which nonexistent doctors are called on to testify or deliberately irrelevant references are bunched up in [fine print], you will find a hundred or more whose greatest offenses are unquestioning enthusiasm and the skill to communicate it.

The best defence the physician can muster against this kind of advertising is a healthy skepticism and a willingness, not always apparent in the past, to do his homework. He must cultivate a flair for spotting the logical loophole, the invalid clinical trial, the unreliable or meaningless testimonial, the unneeded improvement and the unlikely claim. Above all, he must develop greater resistance to the lure of the fashionable and the new.
- Pierre R. Garai (advertising executive) 1963