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Healthy Skepticism Library item: 3783

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Ahlborn H, Henderson S, Davies N.
No immediate pain relief for the pharmaceutical industry.
Curr Opin Drug Discov Devel 2005 May 01; 8:(3):384-91


Abstract:

Over many years, the pharmaceutical industry has developed a highly successful model for making new medicines. Currently, there are an estimated 13,000 prescription drugs on the market. However, the model that has served the sector so well for so long is now breaking down. Lack of productivity in the laboratory, the imminent expiry of patents for numerous best selling products, intense competition and a more demanding marketplace, are all signs of a need for a new approach to drug discovery. Consequently, some pharmaceutical executives may feel that they are managing a previously prestigous team, which now find themselves in the relegation zone, and cannot continue under the same model. This article suggests that radical transformation of the business at every level is the only key to long-term success.

Keywords:
Drug Approval Drug Design Drug Industry/economics* Drug Industry/trends Economic Competition* Economics, Pharmaceutical/trends* Humans Models, Economic

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909