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Healthy Skepticism Library item: 3067

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: news

Gorman B.
Developing Drug Markets
The Motley Fool 2005 Dec 19
http://www.fool.com/News/mft/2005/mft05121924.htm


Notes:

Ralph Faggotter’s Comments:

North America, Japan and the EU ccurrently account for 87% of the global pharmaceutical market, but Asia, Africa, South America and Australia are catching up.


Full text:

Developing Drug Markets

By Brian Gorman
December 19, 2005

When drug companies talk about the global market, they almost invariably mean the “Big Three:” North America, the European Union, and Japan. This is understandable, since together they accounted for roughly 87% of worldwide pharmaceutical sales in 2004, according to IMS Health.

But the world is a dynamic place. Last year, Asia, Africa, and Australia combined were just 7.7% of global sales and Latin America just 3.8%. But think of it in terms of growth, and these parts of the world offer very significant opportunities for investors. These two geographic groupings exhibited the fastest growth at 13.0% and 13.4%, respectively, compared to 7.8% for North America. The developing world appears to offer an attractive niche for companies that can address these markets’ needs. And getting in early could pay off as development continues and opportunities multiply.

One firm that could break into this niche is Acambis (Nasdaq: ACAM). The British drugmaker’s lead candidate is a vaccine in phase 3 trials for Japanese encephalitis (JE). Vaccines for JE have been on the market for 60 years, but the disease remains a major problem in some areas, particularly Asia, where 50,000 cases and 10,000 deaths are reported yearly.

Acambis’ experimental vaccine has some advantages compared to marketed JE vaccines. For one thing, the company expects it will require a single dose compared with multiple doses for existing products. This should be a big plus in the developing world, where patients are less likely or able to return to physicians for multiple doses.

In addition, Acambis’ product will be inexpensive, which is an absolutely vital feature in poorer countries. To keep the price low, Indian biopharmaceutical company Bharat Biotech will package the medicine and market it in India and neighboring countries. India and neighboring Nepal are major potential customers, as more than 1,000 people in the region died from JE from July to November of this year alone.

On the downside, Acambis puts the potential market for the new vaccine at $300 million, which is not huge, although it is significant for the company, given its size. In addition, the firm is a riskier play since it’s unprofitable.

For more risk-averse investors, there are other potential candidates. For example, GlaxoSmithKline (NYSE: GSK) has a malarial vaccine in phase 2 trials, and Sanofi-Aventis (NYSE: SNY) has licensed a phase 1-stage Dengue fever vaccine from Acambis. However investors choose to play it, there seem to be opportunities in drug companies looking toward the developing world.

GlaxoSmithKline is a Motley Fool Income Investor recommendation.

Fools, now is the time to open your hearts and wallets to worthy causes! Please support our five Foolish charities at www.foolanthropy.com.

Fool contributor Brian Gorman is a freelance writer in Chicago. He does not own shares of any companies mentioned in this article.

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909