Healthy Skepticism Library item: 2804

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

Publication type: Journal Article

Dunne M, Newman M, Herxheimer A, Ridley H.
Indications and warnings about chloramphenicol.
Lancet 1973 Oct 6; 2:(7832):781-3

Abstract:

The limited indications for, side-effects of, and contraindications to, chloramphenicol are well established. However, a review of information given on manufacturers’ leaflets for 55 packs available in twenty-one countries highlights wide differences, with unwarranted lists of indications and inadequate (or sometimes no) warnings about the drug’s dangers.

Keywords:
*analytic survey/United Kingdom/United States/Canada/Denmark/Sweden/Thailand/Egypt/Greece/Turkey/New Zealand/Spain/Finland/Switzerland/West Germany/Australia/ Advertising Chloramphenicol/adverse effects* Chloramphenicol/supply & distribution Comparative Study Drug Hypersensitivity/etiology Drug Labeling Drug Packaging Drug and Narcotic Control Europe Europe, Eastern Gastrointestinal Diseases/chemically induced Hematologic Diseases/chemically induced Prescriptions, Drug United States United States Food and Drug Administration

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909