Healthy Skepticism Library item: 2400
Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.
Publication type: Journal Article
Helft PR, Ratain MJ, Epstein RA, Siegler M.
Inside information: Financial conflicts of interest for research subjects in early phase clinical trials.
J Natl Cancer Inst 2004 May 5; 96:(9):656-61
http://jncicancerspectrum.oxfordjournals.org/cgi/content/full/jnci;96/9/656
Abstract:
In recent years, several research subjects have told us that they had bought or intended to buy stock in the companies sponsoring the clinical trials in which they were enrolled. This situation has led us to ask what, if any, are physician-investigators’ scientific, ethical, and legal responsibilities concerning research subjects who choose to buy stock in the companies sponsoring the clinical trials in which they are participating. Although the scope of this problem is unknown and is likely to be small, this commentary examines the scientific, ethical, and legal concerns raised by such activities on the part of research subjects enrolled in early phase clinical trials. In addition, this commentary also outlines the basis for our opinion that research subjects involved in an early phase clinical trial should avoid the financial conflicts of interest created by trading stock in the company sponsoring the clinical trial.
Keywords:
Publication Types:
Review
Review, Tutorial
MeSH Terms:
Clinical Trials, Phase I*/economics
Clinical Trials, Phase I*/ethics
Clinical Trials, Phase I*/legislation & jurisprudence
Conflict of Interest*
Drug Industry*/economics
Drug Industry*/ethics
Drug Industry*/legislation & jurisprudence
Drugs, Investigational*/adverse effects
Drugs, Investigational*/economics
Drugs, Investigational*/standards
Ethics, Research*
Humans
Information Dissemination*/ethics
Information Dissemination*/legislation & jurisprudence
Informed Consent
Physician-Patient Relations
Research Subjects*/economics
Research Subjects*/legislation & jurisprudence
Research Support*
United States
Substances:
Drugs, Investigational
