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Healthy Skepticism Library item: 238

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Wahlbeck K, Adams C.
Beyond conflict of interest: Sponsored drug trials show more-favourable outcomes.
BMJ 1999 Feb 13; 318:(7181):465

Keywords:
*letter to the editor *analytic survey clozapine drug company sponsored research reporting of results clinical trials INFLUENCE OF PROMOTION: OUTCOME OF CLINICAL TRIALS PROMOTION DISGUISED: CLINICAL TRIALS SPONSORSHIP: RESEARCH


Notes:

Trials comparing clozapine with older antipsychotics in schizophrenic patients were analyzed. Trials sponsored by industry favoured clozapine while nonsponsored trials were equivocal. Sponsored trials reported fewer dropouts for clozapine while nonsponsored trials did not find this.

 

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...to influence multinational corporations effectively, the efforts of governments will have to be complemented by others, notably the many voluntary organisations that have shown they can effectively represent society’s public-health interests…
A small group known as Healthy Skepticism; formerly the Medical Lobby for Appropriate Marketing) has consistently and insistently drawn the attention of producers to promotional malpractice, calling for (and often securing) correction. These organisations [Healthy Skepticism, Médecins Sans Frontières and Health Action International] are small, but they are capable; they bear malice towards no one, and they are inscrutably honest. If industry is indeed persuaded to face up to its social responsibilities in the coming years it may well be because of these associations and others like them.
- Dukes MN. Accountability of the pharmaceutical industry. Lancet. 2002 Nov 23; 360(9346)1682-4.