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Healthy Skepticism Library item: 2339

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Tamblyn R, McLeod P, Hanley JA, Girard N, Hurley J.
Physician and practice characteristics associated with the early utilization of new prescription drugs.
Med Care 2003 Aug; 41:(8):895-908
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12886170&query_hl=65


Abstract:

BACKGROUND: Prescription of new drugs contributes to substantial increases in annual drug expenditures. A small proportion of physicians appear to be early users of new prescription drugs and little is known about their characteristics.

OBJECTIVE: To estimate the initial utilization rate of new prescription drugs among physicians, and the physician and practice characteristics associated with early use.

DESIGN: Cumulative prospective assessment over a 5 year period (1989-1994) of new drug utilization rates in a randomly selected cohort of Quebec physicians.

PARTICIPANTS: 1661 physicians and 669,867 elderly patients.

OUTCOME: Prescribing rate of 20 new drugs, in 6 therapeutic categories, to elderly patients in the first 6 months after inclusion in the Quebec formulary.

RESULTS: The 20 new drugs were prescribed by 1.3-22.3% of physicians, and there was an 8 to 17-fold difference in new drug utilization rates among prescribers. Characteristics associated with higher rates of utilization differed for general practitioners and specialists. Male general practitioners, and physicians graduating from the most recently established medical school in the province, had higher rates of new drug utilization, whereas recent graduation was only associated with higher utilization rates among specialists. Practice volume was associated with higher rates of utilization among GPs. For both GPs and specialists, having a high proportion of elderly in one’s practice and a rural or remote practice location was associated with lower utilization rates.

CONCLUSIONS: Physician sex, specialty, medical school, years since graduation, practice location, volume, and relative proportion of elderly in the physician’s practice influence the utilization of new drugs.

Keywords:
MeSH Terms: Age Factors Canada Data Collection/methods Diffusion of Innovation* Drug Utilization/statistics & numerical data* Family Practice/statistics & numerical data Female Humans Male Physician's Practice Patterns/statistics & numerical data* Practice Management, Medical/statistics & numerical data Prescriptions, Drug/economics Prescriptions, Drug/statistics & numerical data* Professional Practice Location/statistics & numerical data Research Support, Non-U.S. Gov't Schools, Medical Sex Factors Specialties, Medical/statistics & numerical data Time Factors

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909