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Healthy Skepticism Library item: 2243

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Loke TW, Koh FC, Ward JE.
Pharmaceutical advertisement claims in Australian medical publications.
Med J Aust 2002 Sep 16; 177:(6):291-3
http://www.mja.com.au/public/issues/177_06_160902/lok10004_fm.html


Abstract:

OBJECTIVE: To determine the quality of claims in advertisements published in Australian medical publications, describe how benefits and harms are presented, and examine the level of underpinning evidence. DESIGN AND SETTING: Audit of a consecutive three-month sample of advertisements appearing in six popular Australian medical publications. MAIN OUTCOME MEASURES: Proportion of advertisements with quantitative information; proportion of claims conveying clinical outcomes; where retrievable, level of underpinning evidence. RESULTS: Of 1504 claims, 855 could be substantiated quantitatively. Of these, 45% were supported by compelling evidence (randomised controlled trials or better). Of 13 claims explicitly reporting quantitative outcomes, none provided the absolute risk reduction or the number needed to treat. CONCLUSIONS: Our audit invites greater diligence by pharmaceutical companies in substantiating their claims and greater vigilance among clinicians when reading them.

Keywords:
Advertising* Australia Data Interpretation, Statistical Deception Disclosure* Drug Evaluation/statistics & numerical data* Drug Industry* Evidence-Based Medicine Humans Periodicals Risk Treatment Outcome content analysis Australia journal advertisements evidence absolute risk reduction number needed to treat EVALUATION OF PROMOTION: JOURNAL ADVERTISEMENTS PROMOTIONAL TECHNIQUES: JOURNAL ADVERTISEMENTS

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909