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Healthy Skepticism Library item: 18915

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Godlee F
Stop exploiting orphan drugs
BMJ 2010 Nov 17; 341:
http://www.bmj.com/content/341/bmj.c6587.extract


Abstract:

The most surprising revelation in this week’s BMJ is that there’s a website that lists drugs that can be “orphaned” and exploited for profit. In an open letter to Britain’s prime minister, 21 neurologists and paediatricians call for an urgent review into the pricing of orphan drugs (doi:10.1136/bmj.c6466). Legislation meant to encourage development of new treatments for rare diseases is instead severely limiting availability of existing treatments, they say, costing the taxpayer unnecessary millions and reaping massive profits for drug companies.

As Nigel Hawkes and Deborah Cohen describe (doi:10.1136/bmj.c6459), a company needs only to find an unlicensed drug and license it for use in a rare condition, citing little more than pre-existing evidence of …

 

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Cases of wilful misrepresentation are a rarity in medical advertising. For every advertisement in which nonexistent doctors are called on to testify or deliberately irrelevant references are bunched up in [fine print], you will find a hundred or more whose greatest offenses are unquestioning enthusiasm and the skill to communicate it.

The best defence the physician can muster against this kind of advertising is a healthy skepticism and a willingness, not always apparent in the past, to do his homework. He must cultivate a flair for spotting the logical loophole, the invalid clinical trial, the unreliable or meaningless testimonial, the unneeded improvement and the unlikely claim. Above all, he must develop greater resistance to the lure of the fashionable and the new.
- Pierre R. Garai (advertising executive) 1963