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Healthy Skepticism Library item: 18915

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Godlee F
Stop exploiting orphan drugs
BMJ 2010 Nov 17; 341:
http://www.bmj.com/content/341/bmj.c6587.extract


Abstract:

The most surprising revelation in this week’s BMJ is that there’s a website that lists drugs that can be “orphaned” and exploited for profit. In an open letter to Britain’s prime minister, 21 neurologists and paediatricians call for an urgent review into the pricing of orphan drugs (doi:10.1136/bmj.c6466). Legislation meant to encourage development of new treatments for rare diseases is instead severely limiting availability of existing treatments, they say, costing the taxpayer unnecessary millions and reaping massive profits for drug companies.

As Nigel Hawkes and Deborah Cohen describe (doi:10.1136/bmj.c6459), a company needs only to find an unlicensed drug and license it for use in a rare condition, citing little more than pre-existing evidence of …

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909