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Healthy Skepticism Library item: 18863

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

John-Baptiste A, Bell C
Industry sponsored bias in cost effectiveness analyses
BMJ 2010 Oct 13; 341:
http://www.bmj.com/content/341/bmj.c5350.extract


Abstract:

Evidence is growing that the involvement of industry in cost effectiveness analyses can affect the findings. A systematic review of published cost-utility analyses found that industry funded studies were more than twice as likely to report a cost-utility ratio below $20 000 (£12 700; $14 850) per quality adjusted life year (QALY) as studies sponsored by non-industry sources.1 The National Institute for Health and Clinical Excellence (NICE) in the United Kingdom found that cost effectiveness analyses submitted by manufacturers produced significantly lower ratios than those derived by assessors at academic centres

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909