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Healthy Skepticism Library item: 17771

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Jakobsen AK, Christensen R, Persson R, Bartels EM, Kristensen LE
And now, e-publication bias
BMJ 2010 Apr 28; 340:
http://www.bmj.com/cgi/content/extract/340/apr28_2/c2243


Abstract:

In open access publishing scholarly communication is made available free of charge on the internet. In biomedical research, authors or sponsors often pay a fee to a publisher to enable immediate free online access.1 2 A few journals operate entirely under this model, whereas others use a hybrid model allowing authors to choose between subscription access and author-paid open access.

We investigated the association between funding of biomedical research by industry and author-paid open access publishing in the Annals of the Rheumatic Diseases, a journal in the BMJ Group. We included extended reports published during October 2007 to September 2008, defining primary exposure as study funding from an industrial source with commercial interests in the area studied, and secondary exposure as other author-industry affiliations. Access (the outcome measure) was defined as locked (subscription access) or unlocked (open access).

Of 216 extended reports, 71 had received funding from an industrial sponsor. . . .

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909