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Healthy Skepticism Library item: 14641

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Lim CW, Kirikoshi T.
Understanding the effects of pharmaceutical promotion: a neural network approach guided by genetic algorithm-partial least squares.
Health Care Manag Sci 2008 Dec; 11:(4):359-72
http://www.ncbi.nlm.nih.gov/pubmed/18998595


Abstract:

With escalating healthcare costs and increasing concerns about optimizing use of medicine, there is an unresolved debate over years around the potential impact of pharmaceutical promotion on physicians’ prescribing behaviors. What should be the appropriate balance of promotion dollars to physicians? We use three major brands in the US antibiotic universe to explore this issue, presenting a theoretical framework for better understanding the cause-and-effect relationship between common promotional spending and prescription responsiveness. Using simulations we demonstrate that neural networks guided by genetic algorithm-partial least squares is able to provide managers with better understanding of physicians’ prescribing activities without an appreciably lower predictive accuracy when compared to that obtained by a standalone neural network modeling.

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909