Healthy Skepticism Library item: 13991

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Publication type: Journal Article

Al-Marzouki S, Roberts I, Evans S, Marshall T.
Selective reporting in clinical trials: analysis of trial protocols accepted by The Lancet
The Lancet 2008 Jul 19; 372:(9634):201
http://www.thelancet.com/journals/lancet/article/PIIS0140673608610600/fulltext

Abstract:

Selective reporting in clinical trials occurs when outcome data are collected but not reported, and when investigators do many analyses but report only the most favourable. It can distort the results of trials1 and bias meta-analyses.2 We studied trial protocols that had been peer reviewed and accepted for publication in The Lancet to examine whether selective reporting of outcomes and subgroup analyses was present…