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Healthy Skepticism Library item: 13681

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Berger E.
Leak: Avandia and the integrity of the peer review process.
Ann Emerg Med 2008 May; 51:(5):636-8
http://www.annemergmed.com/article/S0196-0644(08)00603-3/fulltext


Abstract:

A San Antonio researcher who leaked an unfavorable, prepublication copy of a drug study to its manufacturer has thrust the cozy relationship between pharmaceutical companies and physicians into the spotlight again. The result is another blemish that may undermine public trust in the integrity of medical research.

Whether the current embarrassment leads to reform is unclear, but Congress has begun investigating, and some physicians say this may be just the impetus needed to change the current practice of drug company-funded clinical trials. The issue has broad implications for the peer review process, the very foundation of scientific discourse…

Conflicted Interests
The Ties That Bind
No Quick Fix
Patient Level Data

Keywords:
Publication Types: News MeSH Terms: Conflict of Interest* Drug Industry* Ethics, Medical* Humans Hypoglycemic Agents/adverse effects* Peer Review, Research/ethics* Thiazolidinediones/adverse effects* Substances: Hypoglycemic Agents Thiazolidinediones rosiglitazone


Notes:

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909