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Healthy Skepticism Library item: 12823

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: news

Goldstein J.
Cephalon Marketing Settlement Weighs on Provigil
The Wall Street Journal 2008 Feb 14
http://blogs.wsj.com/health/2008/02/14/cephalon-marketing-settlement-weighs-on-provigil/


Full text:

Cephalon’s deals with generics companies that the FTC claims have delayed cheap alternatives for the drug Provigil are likely to remain in force for a while, analysts say. But a separate government action last year already appears to be weighing on Cephalon’s sales of the anti-drowsiness pill.

Last November, the drugmaker settled state and federal investigations into its marketing practices, which allegedly included promoting drugs for unapproved uses. Cephalon agreed to pay $425 million and abide by a corporate integrity agreement that spells out dos and don’ts for company behavior. What happened next? After climbing for years, new prescriptions for Provigil fell 8% in December compared with same month the year before. And new prescriptions were down again in January, according to IMS Health data cited by Lazard Capital Markets.

“[W]hat is the demand today for Provigil absent all the bonuses and guidance and doctor events and speaker lunches, etc.?” Lazard’s Megan Murphy wrote in a note today. It’s possible that the decline in new prescriptions will persist, hurting sales of the drug, Murphy suggested in a conversation with the Health Blog. “You have a nine-year-old product, which in the pharmaceutical business is ancient history,” she said.

Yes, the settlement may have briefly affected the company’s sales efforts for the drug, Cephalon spokeswoman Sheryl Williams told us. “Was there some disruption?” she said. “Of course there’s disruption when you have those kinds of things going on.”

But she said the company still met its earnings guidance last year, and thinks there’s more growth for Provigil for people with obstructive sleep apnea. To that end, she noted, the company just launched its first direct-to-consumer ad campaign for the drug, with ads showing up in newspapers and magazines around the country.

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909