Healthy Skepticism Library item: 11677
Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.
Publication type: Journal Article
Wehling M.
Translational medicine: can it really facilitate the transition of research "from bench to bedside"?
Eur J Clin Pharmacol 2006 Feb; 62:(2):91-5
http://www.springerlink.com/content/7782201555m7310x/
Abstract:
Translational medicine is intended to facilitate the transition of basic science results to clinical practice, thereby sharing major aspects of clinical pharmacology. Biomarkers need to be developed to achieve this, and their predictive values need to be assessed. Despite all the attempts to increase output from costly pharmaceutical research investments, all stakeholders complain of the decreasing efficiency of drug development processes, and expensive late attritions seem to be seen at increasing rates. How can translational medicine improve this apparent mismatch between effort and tangible result for daily medical practice? What is missing, and where do we stand?
Keywords:
Translational medicine - Biomarkers - Life sciences
MeSH Terms:
Animals
Biological Markers*
Clinical Trials
Drug Design*
Drug Evaluation, Preclinical
Drug Industry/trends*
Humans
Research/trends*
Substances:
Biological Markers
