Healthy Skepticism Library item: 11562

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

Publication type: Journal Article

Grabowski H.
Are the economics of pharmaceutical research and development changing?: productivity, patents and political pressures
Pharmacoeconomics 2004; 22:((2 Suppl 2)):15-24.
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=PubMed&Cmd=ShowDetailView&TermToSearch=15660474

Abstract:

Pharmaceutical research and development (R&D) competition in the 1980s and 1990 s was characterised by rising R&D expenditures, favourable returns to innovators and the introduction of many new classes of drugs with high social benefits. However, in the past 3 years, the number of new drug introductions has been well below the historical trend, while the cost per new drug continues to increase. In addition to lagging R&D productivity, the industry has been characterised by other economic and policy uncertainties. These include a wave of early patent challenges and growing political pressure to contain pharmaceutical expenditures. This paper examines the consequences of these developments.

Keywords:
Publication Types: Review MeSH Terms: Drug Approval/legislation & jurisprudence Drug Approval/methods Drug Industry/economics Drug Industry/methods Drug Industry/trends Economics, Pharmaceutical* Efficiency Humans Patents/legislation & jurisprudence Research/economics* Research/methods Research/trends Technology, Pharmaceutical/economics* Technology, Pharmaceutical/methods Technology, Pharmaceutical/trends