Healthy Skepticism Library item: 11558
Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.
Publication type: Journal Article
Feuerstein GZ, Ruffolo RR.
Discontinued drugs in 2006: cardiovascular drugs translational medicine perspective.
Expert Opin Investig Drugs 2007 Sep; 16:(9):1315-26
http://www.expertopin.com/doi/abs/10.1517/13543784.16.9.1315
Abstract:
This perspective on discontinued cardiovascular drugs is the first in a series of papers on drugs dropped from clinical development in 2006. The compounds described in this perspective have been removed from development in various stages and for different reasons. This paper hereby provides a translational medicine perspective on these compounds based on information available through the Pharmaprojects pipeline database. In particular, potential gaps in the pipeline, due to a lack of biomarkers and translational medicine perspectives are emphasized.
Keywords:
Publication Types:
Review
MeSH Terms:
Animals
Biological Markers/analysis
Cardiovascular Agents/adverse effects*
Cardiovascular Agents/classification
Cardiovascular Agents/standards*
Drug Approval/methods
Drug Industry/methods*
Drug Industry/standards*
Drug Industry/trends
Drugs, Investigational/adverse effects
Drugs, Investigational/classification
Drugs, Investigational/standards
Humans
Substances:
Biological Markers
Cardiovascular Agents
Drugs, Investigational
