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Healthy Skepticism Library item: 11557

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Ozdemir C, Akdis CA.
Discontinued drugs in 2006: pulmonary-allergy, dermatological, gastrointestinal and arthritis drugs.
Expert Opin Investig Drugs 2007 Sep; 16:(9):1327-44
http://www.expertopin.com/doi/abs/10.1517/13543784.16.9.1327


Abstract:

This perspective is the second in a series discussing drugs dropped from development in 2006, with a focus on pulmonary-allergy, dermatological, gastrointestinal and arthritis drugs. A survey of discontinued drugs from 2006 is provided, based on data from the Pharmaprojects database, along with an analysis of biology, mechanisms of action and economic considerations in developing new drugs.

Keywords:
Publication Types: Review MeSH Terms: Animals Anti-Allergic Agents/adverse effects Anti-Allergic Agents/standards* Antirheumatic Agents/adverse effects Antirheumatic Agents/standards* Dermatologic Agents/adverse effects Dermatologic Agents/standards* Drug Approval/methods Drug Industry/methods Drug Industry/standards Drugs, Investigational/adverse effects Drugs, Investigational/standards Gastrointestinal Agents/adverse effects Gastrointestinal Agents/standards* Humans Respiratory System Agents/adverse effects Respiratory System Agents/standards* Substances: Anti-Allergic Agents Antirheumatic Agents Dermatologic Agents Drugs, Investigational Gastrointestinal Agents Respiratory System Agents

 

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Cases of wilful misrepresentation are a rarity in medical advertising. For every advertisement in which nonexistent doctors are called on to testify or deliberately irrelevant references are bunched up in [fine print], you will find a hundred or more whose greatest offenses are unquestioning enthusiasm and the skill to communicate it.

The best defence the physician can muster against this kind of advertising is a healthy skepticism and a willingness, not always apparent in the past, to do his homework. He must cultivate a flair for spotting the logical loophole, the invalid clinical trial, the unreliable or meaningless testimonial, the unneeded improvement and the unlikely claim. Above all, he must develop greater resistance to the lure of the fashionable and the new.
- Pierre R. Garai (advertising executive) 1963