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Healthy Skepticism Library item: 11268

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

O'Dowd A.
Economist says NICE should approve fewer costly drugs
BMJ 2007 Jul 7; 335:(7609):11
http://www.bmj.com/cgi/content/full/335/7609/11-a


Abstract:

A leading economist has recommended that the body that determines which drugs can be prescribed by the NHS in England and Wales should change its threshold, so that fewer expensive drugs are approved.

MPs on the health select committee heard from health economists last week as part of their inquiry into various aspects of the National Institute for Health and Clinical Excellence (NICE), including why its decisions and evaluation process are increasingly being challenged.

Peter Smith, director of the Centre for Health Economics, at the University of York, told MPs that NICE’s current cost effectiveness threshold was between £20 000 and £30 000 (45 000; $60 000) per quality adjusted life year (QALY, a measure of the cost for each extra year lived by a patient treated with the drug in question).

Professor Smith compared the threshold used by NICE for approving drugs to the average cost of saving . . .

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909