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Healthy Skepticism Library item: 10973

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Klein D, MacDonald A, Drummond N, Cave A.
A qualitative study to identify factors influencing COXIB prescribed by family physicians for musculoskeletal disorders.
Fam Pract 2006 Dec; 23:(6):659-65
http://fampra.oxfordjournals.org/cgi/content/full/23/6/659


Abstract:

INTRODUCTION: Cyclo-oxygenase-2 inhibiting (COXIB) anti-inflammatories have been the drug class prescribed for a large number of cases of musculoskeletal (MSK) disorders in Canada over the past 5 years. The Alberta Improvements for MSK Disorders (AIMS) initiative sought to better understand the COXIB prescribing situation by funding several studies. The objective of this qualitative study was to determine the factors underlying primary care physicians’ medication prescribing behaviour during an office visit for an MSK disorder, with particular emphasis on the prescribing of COXIBs.

METHODS: The target respondents were Alberta primary care physicians chosen from a stratified random sample to meet a wide range of characteristics. Individual, semi-structured interviews were used to assess decision pathways in four real cases chosen by the physician. A total of 19 interviews were conducted and analysed using an analytic inductive approach.

RESULTS: Factors judged as being important to decision pathways in relation to COXIB prescribing for MSK disease included safety, patient characteristics, affordability to patients, availability of samples, drug company marketing practices, habit formation, time contstraints, previous clinical experience of doctors and/or patient with certain drugs and doctors’ perception of absolute versus relative risk.

Interpretation. Most physicians preferentially prescribed COXIBs subsequent to a complicated, multifactorial, but essentially patient-centred, decision-making process.

Keywords:
MeSH Terms: Alberta/epidemiology Anti-Inflammatory Agents, Non-Steroidal/therapeutic use Arthritis, Rheumatoid/drug therapy Cyclooxygenase 2 Inhibitors/therapeutic use* Decision Making Family Practice/standards Family Practice/statistics & numerical data* Female Fibromyalgia/drug therapy Humans Interviews Male Musculoskeletal Diseases/drug therapy* Musculoskeletal Diseases/epidemiology Osteoarthritis/drug therapy Physician's Practice Patterns/standards Physician's Practice Patterns/statistics & numerical data* Physicians, Family/statistics & numerical data Qualitative Research Research Design Sprains and Strains/drug therapy Substances: Anti-Inflammatory Agents, Non-Steroidal Cyclooxygenase 2 Inhibitors

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909