Healthy Skepticism Library item: 10904

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

Publication type: Journal Article

Jacobson RM, Targonski PV, Poland GA.
Why is evidence-based medicine so harsh on vaccines? An exploration of the method and its natural biases
Vaccine 2007 April 20; 26:(16):3165-9
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TD4-4MV77FN-4&_user=10&_coverDate=04%2F20%2F2007&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=82a9ce73e292c635280971eb86101b71

Abstract:

Vaccines have been hailed as one of the greatest success stories of public health in the 20th century. The 20th century also produced a call for evidence-based medicine (EBM) with applications inclusive of preventive health. Since then, several major EBM analyses have called into question vaccine practices well-accepted by physicians, public health officials, and even the lay public. For example, while counter to existing studies and policies, EBM analyses have concluded that data are lacking to support influenza vaccination of healthcare workers to prevent flu complications among the elderly. In this review, we examine the criticisms and consider the shortcomings in the field of vaccinology as well as in the methodology of evidence-based medicine.

Keywords:
Drug Approval Drug Industry Evidence-Based Medicine* Humans Vaccines/administration & dosage Vaccines/pharmacology Vaccines/standards* Vaccines/therapeutic use*