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Healthy Skepticism Library item: 10771

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Fugh-Berman A, Bythrow J.
Bioidentical hormones for menopausal hormone therapy: variation on a theme.
J Gen Intern Med 2007 Jul; 22:(7):1030-4
http://www.springerlink.com/content/q4772464371784g2/


Abstract:

BACKGROUND: Progesterone creams and natural or bioidentical compounded estrogen preparations are being promoted to consumers as safe alternatives to conventional menopausal hormone therapy and as health-promoting tonics. No reliable data support these claims.

SAFETY: Natural hormones, including estradiol, estriol, estrone, and progesterone, can be expected to have the same adverse event profile as conventional menopausal hormone regimens.

SALIVARY HORMONE TESTS: Salivary tests may be used to persuade asymptomatic consumers to use hormones (or symptomatic patients to use higher doses than those needed to mitigate symptoms), a practice that can be expected to result in adverse events.

Keywords:
natural hormones - bioidentical hormones - menopausal hormone therapy - topical progesterone cream - estriol - compounding pharmacies - Triest - salivary hormone testing Publication Types: Research Support, Non-U.S. Gov't MeSH Terms: Administration, Cutaneous Advertising Drug Compounding Endometrium/drug effects Estrogen Replacement Therapy/adverse effects* Estrogen Replacement Therapy/contraindications Estrogen Replacement Therapy/ethics Estrogen Replacement Therapy/methods Estrogens/adverse effects Female Humans Menopause* Phytosterols/administration & dosage Phytosterols/adverse effects* Phytosterols/pharmacokinetics Plant Preparations/administration & dosage Plant Preparations/adverse effects* Plant Preparations/pharmacokinetics Saliva/chemistry Self Administration Steroids/adverse effects Therapeutic Equivalency United States United States Food and Drug Administration Vaginal Creams, Foams, and Jellies/adverse effects Substances: Estrogens Phytosterols Plant Preparations Steroids Vaginal Creams, Foams, and Jellies

 

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