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Healthy Skepticism Library item: 10735

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Chen LC, Ashcroft DM, Elliott RA.
Do economic evaluations have a role in decision-making in Medicine Management Committees? A qualitative study
Pharm World Sci. 2007 June 14; [Epub ahead of print]
http://www.springerlink.com/content/d570650707384461/


Abstract:

OBJECTIVE: To explore pharmacists’ perceptions on the use of economic evaluations in decision-making within Medicine Management Committees (MMCs), identify factors that influence the uptake of economic evidence and examine the usefulness of different presentations of economic evidence.

METHOD: This two-stage qualitative study was carried out in July and August 2004 in two hospitals in northwest England. First, a researcher observed the decision-making process at two MMCs. Handwritten notes were made during observation, which were later transcribed. Subsequently, in-depth semi-structured interviews were conducted with a purposive sample of pharmacists involved in the MMCs. The interviews explored pharmacists’ views on the usefulness of economic evaluations in decision-making, the factors influencing the uptake of economic evidence by the MMCs, and the optimal presentation of economic results. The interviews were audiotaped and transcribed verbatim. All the transcribed data were thematically analysed using the constant comparison approach.

RESULTS: In all, six new drug applications were observed and ten pharmacists were interviewed. Pharmacists were observed to play an important role in decisions about drug formularies in hospitals. Although interviewees considered that timely economic evaluations would be useful in reviewing new medicines, the actual use of economic evidence in decision-making within MMCs was limited. The barriers to using economic evaluations included pharmacists’ lack of initiative to search for and difficulty in understanding economic evaluations, and the perceived availability, credibility and transferability of economic studies. However, the main barrier to implementing economic evidence was the decision makers’ concern about the impact of the medicines on the hospitals’ drug budgets. Interviewees felt that they understood and trusted disaggregated economic results better than aggregated ones.

CONCLUSION: This study found the use of economic evidence in decision-making at both MMCs was limited. To improve the usefulness of economic evaluations in MMCs, members of MMCs will need more training in accessing, understanding and appraising economic evidence; researchers need to improve the credibility and transferability of economic studies, and present the results in clear and understandable ways. However, due to the restricted focus of local, short-term drug budgets, evidence-based decision-making remains a challenge for local MMCs.

Keywords:
Budget - Decision-making - Economic evaluations - Health economics - Medicine management committee - United Kingdom

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909