Healthy Skepticism Library item: 6627

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

Publication type: Journal Article

Bero LA, Rennie D.
Influences on the quality of published drug studies.
Int J Technol Assess Health Care 1996 Spr; 12:(2):209-37

Abstract:

To practice evidence-based medicine, physicians need data on clinical effectiveness, toxicity, convenience and cost of new drugs compared with available alternatives. We give examples of published drug studies that are defective, sometimes because pharmaceutical industry funding has affected their content and quality. We make recommendations on how to avoid these defects.

Keywords:
*systematic review/drug company sponsored research/publication bias/randomized controlled trials, evaluation of/INFLUENCE OF PROMOTION: OUTCOME OF CLINICAL TRIALS/INFLUENCE OF PROMOTION: PUBLICATION/PROMOTION DISGUISED: CLINICAL TRIALS/SPONSORSHIP: RESEARCH Data Interpretation, Statistical Drug Evaluation/economics Drug Evaluation/standards* Drug Industry Publishing/standards Research Design/standards Research Support