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Healthy Skepticism Library item: 608

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Macbeth F, Stephens R.
Marketing clinical trials.
Lancet 1996 Jul 13; 348:(9020):111-2

Keywords:
*analysis United Kingdom drug company sponsored research relationship between researchers, academic institutions and industry clinical trials


Notes:

What rewards can and do clinicians get for the obtaining and transfer of patient data in clinical trials. For most doctors the scale of value probably runs: money>resources>esteem>group membership (being part of an organization)>intellectual curiousity; although publicly doctors may still insist that it is the reverse. At the moment many clinicians fund data managers and/or research nurses by undertaking industry-sponsored investigations. Some may be good studies but many are either disguised marketing exercises or ways of getting data for drug licensing, and they are not often subject to rigorous peer review.

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909