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Healthy Skepticism Library item: 5170

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Massie BM, Rothenberg D.
Publication of sponsored symposiums in medical journals.
N Engl J Med 1993 Apr 22; 328:(16):1196-7


Abstract:

The authors studied clinical trials dealing with the medical therapy of angina that were published over a three-year period in eight major peer reviewed journals. There were usually marked differences between industry funded studies and those that received other funding in where the articles were published, whether they were peer reviewed and duplicate publication of articles.

Keywords:
*letter to the editor/sponsored symposia & conferences/journal supplements/publication bias/quality of information/acknowledgement of funding/ corporate funding/ clinical trials/ drug company sponsored research/INFLUENCE OF PROMOTION: OUTCOME OF CLINICAL TRIALS/INFLUENCE OF PROMOTION: PUBLICATION/PROMOTION DISGUISED: JOURNAL SUPPLEMENTS, CONTROLLED CIRCULATION JOURNALS AND NEWSLETTERS


Notes:

Reply to: Lisa A. Bero et al., New England Journal of Medicine 1992;327:1135-1140.
Reply from: Lisa A. Bero et al., New England Journal of Medicine 1992;328:1197-1198.
Methodology note: The methodology is not described in enough detail in this letter to evaluate it

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909