Healthy Skepticism Library item: 4368

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Publication type: Journal Article

Levy G.
Publication bias: its implications for clinical pharmacology.
Clin Pharmacol Ther 1992 Aug; 52:(2):115-9

Abstract:

Publication bias in favour of positive results has been demonstrated a number of times, but there is not enough evidence to justify a definitive conclusion thta the demonstrated bias has been intentional and motivated by self-serving interests of investigators or sponsors. The major source of bias against publishing studies with negative findings is authors. The author offers a number of proposals to mitigate this bias.

Keywords:
*analysis/drug company sponsored research/publication bias/SPONSORSHIP: RESEARCH Clinical Trials/standards* Comparative Study Double-Blind Method Humans Observer Variation* Publishing/standards* Randomized Controlled Trials/standards