Healthy Skepticism Library item: 4227

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

Publication type: Journal Article

Schwarz RP Jr.
Maintaining integrity and credibility in industry-sponsored clinical research.
Control Clin Trials 1991 Dec; 12:(6):753-60

Abstract:

There have been recent, heightened concerns about the integrity and credibility of industry-sponsored clinical research. While attributable to a variety of factors, the potential consequences are a decrease in the ability of the biomedical research enterprise to produce innovative methods for the diagnosis and treatment of disease, with possible adverse implications for the health and well-being of the public. A specific example of a recent industry-sponsored clinical trial is presented as an approach to attempt to avoid any suggestion of fraud, error, or biased interpretation, in a way in which the integrity of the process will not be called into question and the credibility of the results will be maximized.

Keywords:
*analysis/United States/drug company sponsored research/SPONSORSHIP: RESEARCH Cardiotonic Agents/therapeutic use Clinical Trials* Drug Industry* Heart Failure, Congestive/drug therapy Heart Failure, Congestive/mortality Humans Milrinone Prospective Studies Pyridones/therapeutic use Quality Assurance, Health Care* Research Support* Scientific Misconduct* Survival Rate