Healthy Skepticism Library item: 13868

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Publication type: Journal Article

Hankey GJ.
Heparin in acute ischaemic stroke: The T wave is negative and it's time to stop.
Med J Aust. 1998 Nov 16; 169:(10):534-6
http://www.ncbi.nlm.nih.gov/pubmed/9861911

Abstract:

The use of heparin for acute ischaemic stroke has long been controversial. Although it may have some theoretical benefits in preventing fibrin formation and thrombus propagation, data from 16 randomised controlled trials involving more than 22,000 patients show that heparin produces no significant net benefit in eventual outcome.

Keywords:
Acute Disease Attitude of Health Personnel Brain Ischemia/drug therapy* Electroencephalography Fibrinolytic Agents/therapeutic use* Heparin/therapeutic use* Humans Randomized Controlled Trials as Topic Recurrence/prevention & control Treatment Outcome